Episode 191

189. Infinite Threads: Recycling Athleisure Waste with Samsara’s Vanessa Vongsouthi

· 48:34 · Host: Karl Schmieder & Erum Azeez

Vanessa Vongsouthi, Research Founder and Head of Bioengineering at Samsara Eco, joins host Erum on the Grow Everything Podcast to discuss how engineered enzymes and AI are making it possible to recycle textiles and plastics repeatedly. Vanessa explains how Samsara uses AI-assisted protein design…

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Chapters

  1. 00:00:00 — Intro: Heat waves, climate impacts, and the bioeconomy
  2. 00:03:00 — Would Big Tech buy a pharmaceutical company?
  3. 00:08:00 — Brewed human collagen: Gelatech x Hugel partnership
  4. 00:10:00 — France bans fast fashion: Shein, Temu, and the Atacama Desert
  5. 00:13:00 — Introducing Vanessa Vongsouthi of Samsara Eco
  6. 00:17:00 — Biology as future industrial infrastructure
  7. 00:22:00 — Programming enzymes with AI and ancestral sequence reconstruction
  8. 00:29:00 — The Lululemon jacket: proof that enzymatic recycling scales
  9. 00:35:00 — Distributed recycling and a circular material economy
  10. 00:42:00 — Post-interview debrief and key takeaways

Show notes

Vanessa Vongsouthi, Research Founder and Head of Bioengineering at Samsara Eco, joins host Erum on the Grow Everything Podcast to discuss how engineered enzymes and AI are making it possible to recycle textiles and plastics repeatedly. Vanessa explains how Samsara uses AI-assisted protein design and ancestral sequence reconstruction to create enzymes that break down complex polymers, including Nylon 6,6, into their original chemical building blocks. Those materials can then be returned to existing supply chains and used to create virgin-equivalent products that are indistinguishable from materials made from petrochemicals. She also shares the story behind the world’s first enzymatically recycled Nylon 6,6 jacket, created in partnership with Lululemon, and explores how Samsara Eco was built through Main Sequence Ventures’ orchestration model alongside partners such as Woolworths and the Australian National University. The conversation also looks at what a future built around distributed, local recycling infrastructure could mean for designers, manufacturers, consumers, and the global circular economy.

Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and innovators changing the world through biology. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?

Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Chapters:

  • (00:00:00) - Intro: Heat waves, climate impacts, and the bioeconomy
  • (00:03:00) - Would Big Tech buy a pharmaceutical company?
  • (00:08:00) - Brewed human collagen: Gelatech x Hugel partnership
  • (00:10:00) - France bans fast fashion: Shein, Temu, and the Atacama Desert
  • (00:13:00) - Introducing Vanessa Vongsouthi of Samsara Eco
  • (00:17:00) - Biology as future industrial infrastructure
  • (00:22:00) - Programming enzymes with AI and ancestral sequence reconstruction
  • (00:29:00) - The Lululemon jacket: proof that enzymatic recycling scales
  • (00:35:00) - Distributed recycling and a circular material economy
  • (00:42:00) - Post-interview debrief and key takeaways

Links and Resources:

Topics Covered:

enzymatic recycling, nylon 66 recycling, textile waste, circular economy, bioengineering, protein engineering, infinite recycling, sustainable fashion, Lululemon recycled jacket, plastic recycling technology

Have a question or comment? Message us here:

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Music by: Nihilore 

Production by: Amplafy Media

About Grow Everything

Grow Everything reveals the world of biology as technology. Hosts Erum Azeez Khan and Karl Schmieder talk with the founders, scientists, and executives biologizing entire industries — biomaterials from waste, precision fermentation, cultivated food — and unpack how the bioeconomy is solving health and climate challenges. Winner of SynBioBeta's 2026 Impact Award.

See all 202 episodes of Grow Everything →

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